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In addition to NAS and CntL, many other NAS-like enzymes have been identified or proposed in the biosynthesis of structurally diverse metallophores with an amino group serving as the acceptor nucleophile, which underscores the importance of SAM-dependent ACP modification of metallophores in bacteria

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The hypothalamus governs when those pulses occur through two opposing signals: GHRH (growth-hormone-releasing hormone), which stimulates release, and somatostatin, which suppresses it

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